Author

Suhas S. Kharat

Vanderbilt UniversityORCID 0000-0003-2283-7429Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Arun Prakash MishraiD· 1 shared Dillon Dierman· 1 shared Satheesh Kumar SengodaniD· 1 shared Shyam K. SharaniD· 1 shared Stephen D. FoxiD· 1 shared Walter ChaziniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Arun Prakash MishraORCID

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1 paper

Recent·Most cited

Cancer BiologyJournal of Biological ChemistryPeer-reviewedJun 19, 2025

5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells

Suhas S. Kharat, Arun Prakash Mishra, Satheesh Kumar Sengodan…·Shyam K. Sharan

This study shows that 5hmC increases PARP1 trapping on chromatin in olaparib-treated cells, restoring PARP inhibitor sensitivity in BRCA1/2-deficient cancer cells.

5 citations

humanDNA methylation

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