Mesenchymal Igf2 is a major paracrine regulator of pancreatic growth and function
Constanze M. Hammerle, Ionel Sandovici, Gemma V. Brierley, Nicola M. Smith, Warren E. Zimmer, Ilona Zvetkova, Haydn M. Prosser, Yoichi Sekita, Brian Lam, Marcella K.L. Ma, Wendy N. Cooper, Antonio Vidal‐Puig, Susan Elizabeth Ozanne, Gema Medina‐Gómez, Miguel Constância
This study identifies mesenchymal Igf2 as a critical paracrine regulator of pancreatic growth and function through in vivo and ex vivo experiments.
PLoS Genetics · Oct 15, 2020Peer-reviewedDevelopmental Biology