Shuyang Zhao

This study identifies two distinct LAM subtypes and their microenvironmental interactions using multi-omics and spatial transcriptomics, revealing key regulatory networks and potential therapeutic targets.

This study shows PRDM3 and PRDM16 regulate chromatin accessibility to support NKX2-1-driven alveolar epithelial differentiation and function, with loss leading to respiratory failure and lineage infidelity.

The paper constructs a single-cell reference atlas for human and mouse lung tissues to improve cell type annotation and data integration.

This study identifies Npt2b and pulmonary osteoclast-like cells as key regulators of phosphate homeostasis and microlith clearance in PAM.

The paper introduces a web toolset called Lung-at-a-glance to integrate and visualize lung ontology, imaging, and single-cell omics data.