Author
Medical College of WisconsinORCID 0000-0001-6592-0877Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Claudia M. Rohr, Frances Blow, Sang-Kyu Park…·Jonathan S. Marchant
This study uses immunolocalization and single-cell RNAseq to show TRPMPZQ expression in excitable cells and sensory structures across Schistosoma mansoni life stages, with reduced expression in PZQ-resistant strains.
Claudia M. Rohr, Sang-Kyu Park, Kelsilandia Aguiar-Martins…·Jonathan S. Marchant
TRPtracker aggregates TRPMPZQ variants and their PZQ sensitivity data to monitor resistance and support schistosomiasis control strategies.
Logan Elkin, Evgeny G. Chulkov, Jonathan David Enders…·Jonathan S. Marchant
The paper shows clonazepam activates TRPM8 ion channels, which may explain its efficacy in treating burning mouth disorder.
Sushil Kumar, Gihan S. Gunaratne, Jasmine Cornish…·Jonathan S. Marchant
This study shows JPT2, an intrinsically disordered NAADP-binding protein, undergoes liquid-liquid phase separation, forming condensates that recruit components involved in NAADP-evoked Ca2+ signaling.
Duncan Berger, Sang-Kyu Park, Thomas Crellen…·Joanne P. Webster
The paper uses population genomics and functional genetics to identify praziquantel resistance variants in Schistosoma mansoni.
Winka Le Clecʼh, Frédéric D. Chevalier, Ana Carolina Alves de Mattos…·Timothy J. C. Anderson
The paper identifies a transient receptor potential channel (Sm.TRPMPZQ) as the genetic basis for variation in praziquantel response in Schistosoma mansoni.