Author

Damien Crépin

University of SussexORCID 0000-0001-6601-5975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Antony W. OliveriD· 2 shared Jessica BoothiD· 2 shared John SpenceriD· 2 shared Mohan B. RajasekaraniD· 2 shared Abdulrahman AlatawiiD· 1 shared Alex HerbertiD· 1 shared Catherine Tighe· 1 shared Darren Le Grand· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Antony W. OliverORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 7, 2026

Structure-function studies of HRIKD-{triangleup}KI, a Minimal Kinase Domain of Human Heme-Regulated Inhibitor Kinase

Mohan B. Rajasekaran, Jessica Booth, Damien Crépin…·John Spencer

The paper reports the structural analysis of a minimal kinase domain of HRI, showing its ligand-binding conformation and non-productive state, supporting drug discovery for blood cancer.

DOI 10.64898/2026.07.06.735516

humanstructural biology

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Cell BiologyNature CommunicationsPeer-reviewedAug 27, 2025

The Balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells

Róbert Zach, Michael Annis, Sandra M. Martin-Guerrero…·Helfrid Hochegger

This study shows that the balance between B55α and Greatwall expression levels determines cancer cell sensitivity to Greatwall inhibition.

4 citations

humanproteomics

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