Johannes F. Hevler

The paper uses thermal proteome profiling to study how glycosylation affects protein function and stability, finding that sialylation and fucosylation perturbations significantly impact cell surface protein interactions.

This study shows that mice with reduced respirasomes maintain normal bioenergetics and physiology, suggesting respirasomes are not essential for basic function but may have other roles.

The paper identifies a previously overlooked complex between AIFM1 and cytochrome c oxidase using mass spectrometry and proteomic approaches, revealing structural insights and potential roles in OXPHOS and cell death.