Developmental BiologyJCI InsightPeer-reviewed
ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM
Sara González-Hernández, Ryo Sato, Yuya Sato…·Yoh‐suke Mukouyama
This study shows that endothelial Prox1 overexpression disrupts the blood-brain barrier by downregulating BBB-associated genes and Wnt/β-catenin signaling during both embryonic and postnatal stages.
2 citations