Manuel J. Muñoz

This study optimizes CRISPR-Cas13d for RNA targeting in zebrafish by improving gRNA design, nuclear targeting, and computational prediction, reducing collateral effects.

This study shows that inactivating steroid sulfatase in C. elegans extends lifespan and reduces age-related diseases, suggesting potential therapeutic applications for aging.

The paper introduces ASACO, a tool for co-expression analysis of genes across transcriptomics data, identifies host factors involved in SARS-CoV infection, and validates findings against high-throughput screens.

The paper develops a method to analyze essential genes in C. elegans by combining flow cytometry and high-throughput image analysis to sort and study homozygous lethal mutants.