Sven Borchmann

pyfraglib provides a platform for cfDNA fragmentomics analysis, including fragment extraction, feature modeling, cohort comparison, and simulation, and identifies a high-risk subgroup in CNSL patients.

This study develops next-generation CD30CAR-T cells using CRISPR/Cas9 for multiplex editing, showing high potency but risks of translocations with combined knockouts.

The paper analyzes 3000 whole genome sequencing datasets to uncover links between bacteria, viruses, and cancer, identifying novel associations and phenotypic differences.