Jingyu Zhang

The paper shows that EMT paths are influenced by cell cycle phase coupling and highlights the limitations of low-dimensional representations in capturing transition dynamics.

The paper identifies long-range chromosomal loops spanning over 100 Mb and shows they form via multivalent binding, independent of known nuclear structures, suggesting a distributed mechanism for chromosome organization.

The paper develops a live-cell imaging platform to study phenotypic transitions, revealing dynamics missed by snapshot data.

This paper develops a modular Gibson assembly method for efficient and cost-effective CRISPR donor DNA construct generation, showing improved assembly efficiency compared to conventional methods.

The paper shows that TGF-β signaling duration is interpreted through pathway crosstalk that controls SNAIL1 expression.

This study shows that targeting the temporal dynamics of microenvironmental factors can halt tumor migration and overcome tumor heterogeneity.