Author

Simon Ducheix

Centre National de la Recherche ScientifiqueORCID 0000-0001-6676-4263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Bertrand CariouiD· 2 shared Cédric Le MayiD· 2 shared Gilliane ChadeufiD· 2 shared Marie Palard· 2 shared Mikaël CroyaliD· 2 shared Rola Shaaban· 2 shared Samy HadjadjiD· 2 shared Xavier PrieuriD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Bertrand CariouORCID

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2 papers

Recent·Most cited

Tripartite ER-Mitochondria-Lipid Droplets contact sites control adipocyte metabolic flexibility

Marie Palard, Gilliane Chadeuf, Maxime Carpentier, Clotilde C.N. Renaud, Samuel Frey, Mikaël Croyal, Rola Shaaban, Samy Hadjadj, Chloé Cloteau, Naïma El Khallouki, Perrine Bomme, Soazig Le Lay, Manuel Majrouh, Perrine Paul‐Gilloteaux, Alexandre Humbert, , Xavier Prieur

This study shows that Seipin regulates tripartite ER-mitochondria-lipid droplet contact sites, which are critical for adipocyte lipid storage and metabolic flexibility.

The EMBO Journal · Jul 22, 2026Peer-reviewedCell Biology

Comparative Transcriptomic Analysis of Obesity and Lipodystrophy Reveals Shared Mechanisms and Novel Targets in Adipose Tissue Dysfunction

Rola Shaaban, Antoine Rimbert, Yoann Combot, Simon Ducheix, Gilliane Chadeuf, Marie Palard, Mikaël Croyal, Samy Hadjadj, Bertrand Cariou, Cédric Le May, Abdelhalim Larhlimi, Xavier Prieur

This study identifies a shared molecular signature in adipose tissue dysfunction across obesity and lipodystrophy, revealing common metabolic pathways and genetic loci associated with type 2 diabetes.

bioRxiv · Dec 4, 2025 · PreprintPhysiology