Author

Matthew L. Tan

University of MichiganORCID 0000-0002-0176-8615Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adam C. AbrahamiD· 2 shared Avinava RoyiD· 2 shared Claudia LoebeliD· 2 shared Adrian A. ShimpiiD· 1 shared Brendon M. BakeriD· 1 shared Claudia FischbachiD· 1 shared Deepak NagrathiD· 1 shared Donia W AhmediD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Adam C. AbrahamORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Local photo-crosslinking of native tissue matrix regulates cell function

Donia W Ahmed, Matthew L. Tan, Yuchen Liu, Jackson Gabbard, Esther Gao, Avinava Roy, Michael M. Hu, Firaol S. Midekssa, Miriam Stevens, Fulei Wuchu, Minal Nenwani, Jingyi Xia, Adam C. Abraham, Deepak Nagrath, Lin Han, , Claudia Loebel

This study uses photo-crosslinking to induce early fibrotic changes in ex vivo tissue, showing how matrix stiffening affects cell behavior and fibrosis progression.

Nature Materials · Sep 5, 2025Peer-reviewedBioengineering

Hydrogel viscoelasticity modulates cell nascent extracellular matrix deposition

Matthew L. Tan, Avinava Roy, Eleanor M. Plaster, Haguy Wolfenson, Adam C. Abraham, Claudia Loebel

This study shows that high-viscosity hydrogels lead to increased nascent extracellular matrix deposition by cells, independent of intracellular contractility.

Macromolecular Rapid Communications · Aug 14, 2025Peer-reviewedBioengineering

Assessing cellular metabolic dynamics with NAD(P)H fluorescence polarization imaging

Ling Lu, Jack C. Crowley, Matthew L. Tan, Jennie A. M. R. Kunitake, Adrian A. Shimpi, Rebecca M. Williams, Lara A. Estroff, Claudia Fischbach, Warren R. Zipfel

This paper introduces FPRM, a fast, label-free imaging method to monitor cellular metabolism using NAD(P)H autofluorescence, and demonstrates its application in tracking metabolic changes under various perturbations.

bioRxiv · Jul 28, 2025 · PreprintBiophysics