Developmental BiologyCellPeer-reviewed
Patterning and folding of intestinal villi by active mesenchymal dewetting
Tyler R. Huycke, Teemu J. Häkkinen, Hikaru Miyazaki…·Zev J. Gartner
This study identifies an active mechanical mechanism involving PDGFRA+ mesenchymal cells that pattern and fold intestinal villi through myosin II-dependent forces and matrix metalloproteinase-mediated tissue fluidization.
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