Katherine I. Albanese

The paper designs de novo all-α-helical proteins using computational methods and validates their stability and structure.

This paper designs 3-helix bundle peptides and proteins with controlled topology and stability using computational methods and experimental validation.

This paper designs A3B3 heterohexameric alpha-helical barrels by controlling heptad register, showing that it affects helix orientation and using AlphaFold-Multimer for modeling.

This paper describes a computational method for designing -helical-barrel proteins with small molecule-binding channels, achieving high expression and structural accuracy in E. coli.

The paper designs synthetic proteins by deriving sequence-to-structure rules from coiled-coil tetramers and validates them through experimental methods.