Cancer BiologybioRxivPreprint
LncRNA-mediated organization of oncogenic chromatin state is a targetable vulnerability in leukemia
Ly Vu, Zhen Jin, Brenda Ma…·Pieter R. Cullis
This study identifies PAN3-AS1 as an oncogenic lncRNA in AML, shows its role in chromatin organization, and demonstrates RNA-targeting LNP therapy to reduce leukemia burden.