Niven R. Narain

MEBOCOST infers metabolite-mediated cell communications from single-cell RNA-seq data, identifying known and novel interactions in mouse brown adipose tissue.

The paper identifies linoleic acid diols that inversely associate with BMI and activate adipocyte calcium fluxes using a novel tool called ScreenDMT.

The paper identifies and validates a biomarker panel combining N-acetylputrescine with clinical features for Parkinson's disease diagnosis, showing high diagnostic accuracy.

This study shows that malignant glioma cells rely on amino acid and glucose fermentation for ATP production, not oxidative phosphorylation, and that glutamine is essential for maintaining ATP content and viability.

The paper analyzes multi-omic data from stressed mice to identify molecular disruptions linked to depression and shows antidepressants reverse these changes in specific brain regions.