H. Y. Li

Erythrocyte signalling is critical for Plasmodium falciparum invasion

This study shows that Plasmodium falciparum merozoite invasion depends on host cAMP-Ca2+ signalling, with RH5-Basigin interaction triggering cAMP rise and Ca2+ influx.

Genomic, transcriptomic, and metabolomic analysis of Traditional Chinese Medicine plant Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti-cancer metabolites

This study identifies ursolic acid as the main anti-cancer compound in Oldenlandia corymbosa and reveals its mode of action through genomic, transcriptomic, and metabolomic analysis.

High-throughput 3D tracking reveals the importance of near wall swimming and initial attachment behaviors of P. aeruginosa for biofilm formation on a vertical wall

This study uses light sheet microscopy to analyze near wall swimming behavior of P. aeruginosa and its mutants, revealing how these behaviors influence initial attachment and biofilm formation on vertical surfaces.

Cancer Cell Intrinsic Expression of MHCII Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma

This study shows that cancer cell expression of MHCII affects T cell infiltration and response to anti-PD-1 therapy in lung adenocarcinoma.

Tumor-Intrinsic Response to IFNgamma Shapes the Tumor Microenvironment and Anti-PD-1 Response in NSCLC

This study identifies tumor-intrinsic IFN-gamma signaling as a determinant of anti-PD-1 response in NSCLC by altering the tumor microenvironment.