Author

Javed Naim Agrewala

Indian Institute of Technology RoparORCID 0000-0001-6786-3239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Akil AkhtariD· 1 shared Anish SuriiD· 1 shared Gordon James FreemaniD· 1 shared Masao HashimotoiD· 1 shared Mohammad Affan KhaniD· 1 shared Natasha M. Girgis· 1 shared Rafi AhmediD· 1 shared Simon LowiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Akil AkhtarORCID

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1 paper

Recent·Most cited

Simultaneous TCR and IL-2 agonism selectively enhances epitope-specific CD8 T cell responses during chronic viral infection

Masao Hashimoto, Mohammad Affan Khan, Akil Akhtar, Javed Naim Agrewala, Gordon James Freeman, Natasha M. Girgis, Yu Zhang, Simon Low, Steven N. Quayle, Anish Suri, Rafi Ahmed

This study shows that targeting IL-2 to antigen-specific CD8 T cells enhances their responses during chronic viral infection while sparing non-targeted populations, and combining this with PD-1 blockade further improves outcomes.

Journal of Virology · Jun 15, 2026Peer-reviewedImmunology