Author

Mohammad Affan Khan

Indian Institute of Technology RoparORCID 0009-0009-5873-1125Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Akil AkhtariD· 1 shared Anish SuriiD· 1 shared Gordon James FreemaniD· 1 shared Javed Naim AgrewalaiD· 1 shared Masao HashimotoiD· 1 shared Natasha M. Girgis· 1 shared Rafi AhmediD· 1 shared Simon LowiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Akil AkhtarORCID

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1 paper

Recent·Most cited

ImmunologyJournal of VirologyPeer-reviewedJun 15, 2026

Simultaneous TCR and IL-2 agonism selectively enhances epitope-specific CD8 T cell responses during chronic viral infection

Masao Hashimoto, Mohammad Affan Khan, Akil Akhtar…·Rafi Ahmed

This study shows that targeting IL-2 to antigen-specific CD8 T cells enhances their responses during chronic viral infection while sparing non-targeted populations, and combining this with PD-1 blockade further improves outcomes.

DOI 10.1128/jvi.00593-26

mouseexperimental assay

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