This study shows that kinetochore proteins in Drosophila and human cells support Golgi assembly and microtubule dynamics in quiescent neural stem cells.

bioRxiv · May 24, 2026 · PreprintNeuroscience

Astrocytes control quiescent NSC reactivation via GPCR signaling-mediated F-actin remodeling

Kun‐Yang Lin, Mahekta R. Gujar, Jiaen Lin, Wei Yung Ding, Jiawen Huang, Yang Gao, Ye Sing Tan, Xiang Teng, Low Siok Lan Christine, Pakorn Kanchanawong, Yusuke Toyama, Hongyan Wang

This study identifies a GPCR signaling pathway in astrocytes that regulates F-actin remodeling and NSC reactivation through Mrtf nuclear translocation.

Science Advances · Jul 24, 2024Peer-reviewedDevelopmental Biology

Arl2 Associates with Cdk5rap2 to Regulate Cortical Development via Microtubule Organization

Dongliang Ma, Kun‐Yang Lin, Suresh Divya, Jiaen Lin, Mahekta R. Gujar, Htet Yamin Aung, Ye Sing Tan, Yang Gao, Anselm Salvatore Vincent, Teng Chen, Hongyan Wang

This study shows that Arl2 regulates mouse cortical development by promoting microtubule growth through its interaction with Cdk5rap2.

bioRxiv · Jan 16, 2024 · PreprintNeuroscience

UNC-6/Netrin and its Receptors UNC-5 and UNC-40/DCC Control Growth Cone Polarity, Microtubule Accumulation, and Protrusion

Mahekta R. Gujar, Lakshmi Sundararajan, Aubrie M. Stricker, Erik A. Lundquist

This paper investigates how UNC-6/Netrin and its receptors UNC-5 and UNC-40/DCC regulate growth cone polarity, microtubule organization, and protrusion during axon guidance in C. elegans.

Genetics · Jul 25, 2018Peer-reviewedNeuroscience