Charlotte Steenblock

Phaeochromocytomas and paragangliomas harbour tumour-initiating SOX2+ stem cells

This study identifies SOX2+ cells in phaeochromocytomas and paragangliomas as potential tumour-initiating stem cells capable of expansion and metastasis.

SOX2+ sustentacular cells are stem cells of the postnatal adrenal medulla

This study identifies SOX2+ sustentacular cells as stem cells for postnatal adrenal medulla chromaffin cells, showing their ability to generate both adrenaline and noradrenaline lineages and maintain homeostasis via WNT6 secretion.

In vitro differentiation of mouse pluripotent stem cells into glucocorticoid-producing adrenocortical cells

This study develops a step-wise in vitro differentiation system from mouse embryonic stem cells into glucocorticoid-producing adrenocortical cells using fibronectin and cAMP activators.