Martin J. Boulanger

This study engineers T cells to respond to G-CSF instead of IL-2, enabling effective melanoma treatment without lymphodepletion or IL-2.

This paper identifies UCB-9721 as a potent inhibitor of T. gondii MyoA, showing greater potency than KNX-002 and inhibiting related apicomplexan parasites.

This study identifies Hp-FAR-2, a secreted fatty acid- and retinol-binding protein from H. polygyrus, which suppresses macrophage polarization by modulating both M1 and M2 markers, potentially aiding parasite persistence.

This study shows parasitic nematode fatty acid- and retinol-binding proteins (FARs) suppress host immunity by modulating lipid signaling pathways and reducing antimicrobial peptide production in flies.

The paper identifies and characterizes a novel family of invariant surface proteins in the metacyclic stage of Trypanosoma brucei, suggesting a more permissive VSG coat structure that may aid vaccine development.