Anna B. Buchman

Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways

This study shows parasitic nematode fatty acid- and retinol-binding proteins (FARs) suppress host immunity by modulating lipid signaling pathways and reducing antimicrobial peptide production in flies.

Genetically Encoded CRISPR components Yield Efficient Gene Editing in the Invasive Pest, Drosophila suzukii

The paper develops transgenic Drosophila suzukii strains expressing Cas9 with different promoters and terminators to enable efficient gene editing for studying gene function and control strategies.

Inherently confinable split-drive systems in Drosophila

This study tests split gene-drive systems in Drosophila that target essential genes, showing variable copy efficiencies and sex-biased transmission, with outcomes that can be inherently confined.

Assessment of a split homing based gene drive for efficient knockout of multiple genes

This study evaluates a split homing gene drive in Drosophila to simultaneously target two genes, showing high disruption efficiency but also resistance allele accumulation.

Live calcium imaging of Aedes aegypti neuronal tissues reveals differential importance of chemosensory systems for life-history-specific foraging strategies

The paper uses live calcium imaging in Ae. aegypti larvae to study sensorimotor responses and foraging strategies, revealing the role of chemosensory systems.

Engineered resistance to Zika virus in transgenic Ae. aegypti expressing a polycistronic cluster of synthetic miRNAs

This study generates Ae. aegypti mosquitoes engineered with synthetic miRNAs to reduce ZIKV infection, dissemination, and transmission.

Site-specific transgenesis of the D. melanogaster Y-chromosome using CRISPR/Cas9

This paper describes a CRISPR/Cas9-based method for site-specific transgenesis on the D. melanogaster Y-chromosome and demonstrates its application in detecting chromosomal nondisjunction.

Synthetically Engineered Medea Gene Drive System in the Worldwide Crop Pest, D. suzukii

The paper develops a synthetic Medea gene drive in D. suzukii, showing high inheritance bias but noting resistance and fitness costs that limit its spread.