Yukihiko Sugita

This study reveals how rabies virus P protein inhibits interferon signaling by selectively binding to phosphorylated STAT1 tetramers, stabilizing them and preventing DNA binding.

This study determines the structure of BoDV-1 nucleoprotein-RNA complexes using cryo-EM, revealing RNA-independent assembly mechanisms and conserved features across the Bornaviridae family.

This study shows how thermally tunable heterodimeric linkers can control the morphology of protein tubes by altering their thermal transition behaviors and enabling multi-walled structures.

This study investigates the structural dynamics of the human KOR-Gi signaling complex with G-protein-biased and balanced agonists, identifying key residues involved in signaling bias.

This study presents the cryo-EM structure of the PINK1-HSP90-CDC37 complex, revealing how HSP90-CDC37 stabilizes PINK1 and how mutations may disrupt this process.

This paper introduces NIPAD, a method to design two-component tubular protein assemblies that mimic biological structures like actin and microtubules, showing dynamic flexibility and reversible assembly.

This study determines the structure of the Ebola virus nucleocapsid using cryo-EM and identifies VP24's role in assembly and function.

The paper determines the structures of intermediate stages of pore formation by the Iota toxin's membrane-binding component using cryo-EM, revealing a stepwise maturation mechanism.