Mika Hirose

This study reveals how rabies virus P protein inhibits interferon signaling by selectively binding to phosphorylated STAT1 tetramers, stabilizing them and preventing DNA binding.

This study identifies LipL32 as a key structural protein in Leptospira interrogans that maintains cell-envelope integrity and stiffness, affecting pathogenicity.

This study investigates the structural dynamics of the human KOR-Gi signaling complex with G-protein-biased and balanced agonists, identifying key residues involved in signaling bias.

The paper determines the structure of the Na+-driven stator PomAB from Vibrio using cryo-EM and reveals the sodium ion pathway, ion selectivity mechanism, and inhibition by phenamil.

The paper determines the Cryo-EM structure of PPARγ in complex with Transportin-1, revealing a non-canonical NLS recognition mechanism.

The paper reports the near-atomic structure of the S-ring from Vibrio alginolyticus flagellar motor using cryo-EM, revealing structural differences compared to Salmonella.

This study shows that certain SARS-CoV-2 antibodies enhance infection by cross-linking spike proteins, causing NTD-RBD domain decoupling without needing the Fc region.

The paper uses a convolutional neural network to classify antibiotic-resistant E. coli cells in TEM images based on morphological features, achieving 94% accuracy.