Author

Burak Toprakhisar

Leuven Stem Cell InstituteORCID 0000-0001-6890-1401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Catherine M. VerfaillieiD· 2 shared Rodrigo Madeiro da CostaiD· 2 shared Ayla Smout· 1 shared Birhanu BelayiD· 1 shared Elise Anne van OsiD· 1 shared Giulia ChiesaiD· 1 shared Guillem García-LlorensiD· 1 shared Irene TalóniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

Catherine M. VerfaillieORCID

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2 papers

Recent·Most cited

BioengineeringBiofabricationPeer-reviewedApr 15, 2026

Organobodies: A robust and size-controllable system for generating scalable hiPSC-derived liver organoids for drug toxicity screening

Mostafa Kiamehr, Stefano Manzini, Burak Toprakhisar…·Catherine M. Verfaillie

This paper introduces a scalable 3D liver model using hiPSC-derived organoids to predict drug toxicity, showing comparable functionality to primary hepatocytes.

2 citations

humanbulk RNA-seq

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Developmental BiologyCell Death and DiseasePeer-reviewedJan 14, 2021

PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells

Jonathan De Smedt, Elise Anne van Os, Irene Talón…·Catherine M. Verfaillie

The paper introduces a computational tool to identify key transcription factors in lineage specification and validates PU.1 as a master regulator for generating LSEC-like cells from pluripotent stem cells.

39 citations

humanscRNA-seq

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