Araceli Garcia-Mora

Functional recruitment of astrocyte-derived neurons into the mouse visual cortex

This study shows that astrocytes can be converted into functional neurons in the mouse visual cortex, which can integrate into cortical circuits and respond to visual stimuli.

Dlx2 reprograms the transcriptome and laminar position of glia-derivedAscl1-induced interneurons

This study shows that a modified Ascl1 variant, Ascl1SA6, can reprogram glial cells into interneurons that resemble canonical cortical interneurons when combined with Dlx2, improving their laminar positioning.

The evolutionary ancient MEIS transcription factors actuate lineage-specific transcription to establish cardiac fate

The paper shows MEIS transcription factors are essential for activating cardiac-specific gene expression by working with lineage-restricted TFs to drive cardiac differentiation.

Systematic analysis of transcription factor combinatorial binding uncovers TEAD1 as an antagonist of tissue-specific transcription factors in human organogenesis

The paper identifies TEAD1 as a repressor of tissue-specific transcription factors in human organ development by analyzing combinatorial TF binding in enhancers.