Haguy Wolfenson

The paper shows that adhesion assembly, F-actin accumulation, and force generation follow the same time evolution at adhesion sites, with F-actin retrograde flow being faster and not slowing over maturing adhesions.

FibroSight is a deep learning platform that quantifies lung remodeling in ILD histology, showing strong correlation with expert scoring and distinguishing fibrotic from inflammatory changes.

This study identifies smooth muscle cells as the primary initiators of hypertension-mediated cardiac fibrosis through ECM-dependent mechanical processes, independent of fibroblasts.

This study investigates the mechanisms of TAZ biomolecular condensate assembly and maturation, revealing their dynamic nature and role in cellular processes.

This paper develops synthetic exosomes with optimized lipid profiles to enhance gemcitabine delivery in pancreatic cancer, showing improved tumor targeting and treatment efficacy.

This study shows that high-viscosity hydrogels lead to increased nascent extracellular matrix deposition by cells, independent of intracellular contractility.

This study shows that indole, a gut microbiota-derived metabolite, is initially toxic to Entamoeba histolytica but adaptation leads to increased virulence and stress resistance.

This study shows that enteropathogenic Escherichia coli enhances Entamoeba histolytica motility on fibronectin-rich substrates by reducing traction forces and altering F-actin distribution.

This study uses micropillar arrays to analyze F-actin polymerization dynamics in mouse embryonic fibroblasts, revealing synchronized adhesion site communication through spatiotemporal analysis.