Eleanor M. Plaster

The paper shows that nascent extracellular matrix converts hydrogel chemical cues into cell fate decisions, with low modification promoting differentiation and high modification promoting proliferation.

This study shows that high-viscosity hydrogels lead to increased nascent extracellular matrix deposition by cells, independent of intracellular contractility.

This study develops a Matrigel-free method using synthetic hydrogels to form alveolar organoids, showing they secrete their own extracellular matrix for growth.

This study quantifies matrix deposition by muscle stem cells during activation using engineered hydrogels and shows it is critical for maintaining stem cell function.