John William Christman

The paper develops a cell-based platform to generate Resolvin-loaded extracellular vesicles that reduce pulmonary inflammation in mice.

This study shows that myeloid-specific TFAM deficiency causes mitochondrial DNA stress and worsens allergic airway inflammation in mice.

This study shows that overexpressing miR-146a via nanoparticles reduces lung injury during mechanical ventilation by targeting mechanotransduction in macrophages.

This study shows that mTORC1 activation during mechanical ventilation worsens lung injury in ARDS and that inhibiting mTORC1 can prevent ventilator-induced lung injury.