Carolina Rios-Martinez

Stable epigenetic states set single-cell activation thresholds in mammalian expression systems

The paper shows that single-cell gene expression responses in mammalian systems are all-or-none due to stable epigenetic variability, not bursty transcription or bistability.

Single-cell chromatin state transitions during epigenetic memory formation

The paper investigates chromatin state transitions during epigenetic memory formation by analyzing single-cell gene expression and chromatin structure changes after repressor recruitment and release.

Single-molecule chromatin configurations link transcription factor binding to expression in human cells

This study links transcription factor binding to gene expression by analyzing chromatin configurations using single-molecule footprinting in human cells.

Deep self-supervised learning for biosynthetic gene cluster detection and product classification

This paper introduces a self-supervised learning approach to detect and classify biosynthetic gene clusters in microbial genomes using masked language models trained on protein domains.