Author

Diwen Yang

University of TorontoORCID 0000-0001-6951-9298Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A.M. EdwardsiD· 2 shared Aiping DongiD· 2 shared C.H. ArrowsmithiD· 2 shared Hui PengiD· 2 shared Jianxian SuniD· 2 shared Levon HalabelianiD· 2 shared Rachel HardingiD· 2 shared Tyler S. BeyettiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

A.M. EdwardsORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyProceedings of the National Academy of SciencesPeer-reviewedJun 5, 2026

High-throughput protein target mapping enables accelerated bioactivity discovery for ToxCast and PFAS compounds

Diwen Yang, Xiaoyun Wang, Jiabao Liu…·Hui Peng

The paper uses high-throughput affinity-selection mass spectrometry to identify protein targets of ToxCast and PFAS compounds, discovering novel interactions and revealing distinct binding patterns of legacy and replacement PFAS.

4 citationstop 3%

humanproteomics

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Pharmacology & ToxicologyNature CommunicationsPeer-reviewedDec 17, 2025

Enantioselective Protein Affinity Selection Mass Spectrometry (E-ASMS)

Xiaoyun Wang, Jianxian Sun, Shabbir Ahmad…·Levon Halabelian

This study introduces E-ASMS, a method to detect weak binders and assess enantioselectivity, identifying 16 binders across 12 human protein targets with confirmed binding mechanisms.

9 citations

humanproteomics

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