BioengineeringNature CommunicationsPeer-reviewed
✦ In-depth digest
Protein corona formed on lipid nanoparticles compromises delivery efficiency of mRNA cargo
Elizabeth Voke, Mariah Lynn Arral, Henry John Squire…·Markita Patricia Landry
A 16-hour continuous iodixanol density gradient workflow isolates lipid nanoparticle protein coronas from human plasma and shows that vitronectin and C-reactive protein coronas impair mRNA delivery in liver cells.
129 citationstop 1%