Henry John Squire

A 16-hour continuous iodixanol density gradient workflow isolates lipid nanoparticle protein coronas from human plasma and shows that vitronectin and C-reactive protein coronas impair mRNA delivery in liver cells.

The paper identifies plant homeoprotein third alpha helices that can penetrate plant cells, similar to animal homeoproteins, and demonstrates their use for cytosolic delivery of proteins.

This study uses a nano-omic approach with gold nanoparticles to detect early stress biomarkers in Arabidopsis thaliana infected by bacterial pathogens, improving sensitivity over conventional proteomics.