Author

Gerald Wirnsberger

Apeiron Biologics (Austria)ORCID 0000-0001-7035-7038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:protein structure prediction· 2 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Astrid HagelkrüysiD· 4 shared Johannes StadlmanniD· 4 shared Josef Martin PenningeriD· 4 shared Stefan MereiteriD· 4 shared Alì MirazimiiD· 3 shared Chris OostenbrinkiD· 3 shared Max J. KellneriD· 3 shared Vanessa MonteiliD· 3 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMolecular Biology

Astrid HagelkrüysORCID

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4 papers

Recent·Most cited

Molecular BiologyEMBO Molecular MedicinePeer-reviewedJul 4, 2022

Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants

Vanessa Monteil, Brett Eaton, Elena N. Postnikova…·Josef Martin Penninger

This paper shows that clinical-grade soluble ACE2 effectively inhibits multiple SARS-CoV-2 variants, including VOCs, in cell cultures and across independent labs.

59 citationstop 2%

humanexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintDec 25, 2021

Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections

Vanessa Monteil, Stéphanie Devignot, Jonas Klingström…·Alì Mirazimi

The paper shows clinical grade recombinant ACE2 effectively neutralizes SARS-CoV-2 Omicron in VeroE6 cells, outperforming neutralization against reference isolates.

6 citations

humanexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 9, 2021

FIBCD1 is a Conserved Receptor for Chondroitin Sulphate Proteoglycans of the Brain Extracellular Matrix and a Candidate Gene for a Complex Neurodevelopmental Disorder

Christopher W. Fell, Astrid Hagelkrüys, Ana Cicvaric…·Vanja Nagy

This study identifies FIBCD1 as a conserved receptor for chondroitin sulphate proteoglycans in the brain ECM, linking it to neurodevelopmental disorders through genetic and functional analyses.

2 citations

mouseDrosophila

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Molecular BiologyThe EMBO JournalPeer-reviewedAug 10, 2021

Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites

David Hoffmann, Stefan Mereiter, Yoo Jin Oh…·Josef Martin Penninger

The paper identifies two lectins, Clec4g and CD209c, that bind to conserved glycosylation sites on SARS-CoV-2 Spike and reduce viral infections.

80 citationstop 4%

humanproteomics

𝕏 PostBluesky