Author

Chris Oostenbrink

BOKU UniversityORCID 0000-0002-4232-2556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alì MirazimiiD· 3 shared Astrid HagelkrüysiD· 3 shared Gerald WirnsbergeriD· 3 shared Johannes StadlmanniD· 3 shared Josef Martin PenningeriD· 3 shared Max J. KellneriD· 3 shared Stefan MereiteriD· 3 shared Vanessa MonteiliD· 3 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Alì MirazimiORCID

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3 papers

Recent·Most cited

Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants

Vanessa Monteil, Brett Eaton, Elena N. Postnikova, Michael J. Murphy, Benedict Braunsfeld, Ian Crozier, Franz Kricek, Janine Niederhöfer, Alice Schwarzböck, Helene Breid, Stéphanie Devignot, Jonas Klingström, Charlotte Thålin, Max J. Kellner, Wanda Christ, , Josef Martin Penninger

This paper shows that clinical-grade soluble ACE2 effectively inhibits multiple SARS-CoV-2 variants, including VOCs, in cell cultures and across independent labs.

EMBO Molecular Medicine · Jul 4, 2022Peer-reviewedMolecular Biology

Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections

Vanessa Monteil, Stéphanie Devignot, Jonas Klingström, Charlotte Thålin, Max J. Kellner, Wanda Christ, Sebastian Havervall, Stefan Mereiter, Sylvia Knapp, Núria Montserrat, Benedict Braunsfeld, I. Kozieradzki, Omar Hasan Ali, Astrid Hagelkrüys, Johannes Stadlmann, , Alì Mirazimi

The paper shows clinical grade recombinant ACE2 effectively neutralizes SARS-CoV-2 Omicron in VeroE6 cells, outperforming neutralization against reference isolates.

bioRxiv · Dec 25, 2021 · PreprintMolecular Biology

Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites

David Hoffmann, Stefan Mereiter, Yoo Jin Oh, Vanessa Monteil, Elizabeth Elder, Rong Zhu, Daniel Canena, Lisa Hain, Elisabeth Laurent, Clemens Grünwald‐Gruber, Miriam Klausberger, Gustav Jonsson, Max J. Kellner, Maria Novatchkova, Melita Ticevic, , Josef Martin Penninger

The paper identifies two lectins, Clec4g and CD209c, that bind to conserved glycosylation sites on SARS-CoV-2 Spike and reduce viral infections.

The EMBO Journal · Aug 10, 2021Peer-reviewedMolecular Biology