Joana Paes de Faria

This study shows that Rac1 inhibition prevents cytoskeletal dysfunction in ATTRv-PN by rescuing axonal defects in mice and supporting its therapeutic potential in patients.

This paper identifies KIF4A as a dual regulator of axonal regeneration in adult nervous systems, functioning in neurons and proliferative Schwann cells during injury.

This study identifies Pinch2 as a critical regulator of central nervous system myelination, showing that its loss leads to hypermyelination and pathological myelin outfoldings.

The paper compares the proteome of remyelination and developmental myelination in mice, finding distinct protein compositions and identifying potential therapeutic targets.