Author

David A. Williams

Broad InstituteORCID 0000-0001-7057-6863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Archana Verma· 1 shared Christian BrendeliD· 1 shared Daniel E. BaueriD· 1 shared Daniela Abriss· 1 shared Danilo PelliniD· 1 shared David G. JustusiD· 1 shared Esther MintzeriD· 1 shared Hye Young JiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Archana Verma

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1 paper

Recent·Most cited

GeneticsCell stem cellPeer-reviewedDec 12, 2024

Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells

Jing Zeng, My Anh Nguyen, Pengpeng Liu…·Daniel E. Bauer

This study shows that gene editing of HSCs without ex vivo culture reduces genotoxicity while maintaining therapeutic efficacy for beta-hemoglobinopathy treatment.

34 citationstop 3%

humanCRISPR screen

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