Andreas Tiffeau-Mayer

This study analyzes T cell receptor repertoires in blood and tonsils, finding low clonal sharing and tissue-specific diversity, emphasizing the need for tissue-based analysis.

The paper quantifies T cell response dynamics during primary SARS-CoV-2 infection, showing clone-intrinsic properties drive clonal kinetics and providing insights for vaccine design.

The paper tracks T cell responses over time in the tuberculin skin test to identify Mtb-reactive T cell metaclones that are immunodominant across individuals.

This study systematically analyzes CDR contacts and sequence constraints between TCR αβ chains using TCR structures and mutual information, showing sequence dependencies and co-evolution patterns.