Author

Hiroyasu Aoki

St. Jude Children's Research HospitalORCID 0000-0001-7068-715XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Kouji MatsushimaiD· 2 shared Satoshi UehaiD· 2 shared Shigeyuki ShichinoiD· 2 shared Bin WuiD· 1 shared Chang-Yu CheniD· 1 shared David BendingiD· 1 shared Eiji SugiharaiD· 1 shared Haru OgiwaraiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Kouji MatsushimaORCID

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedOct 20, 2025

LAG-3 blockade reactivates the CD8+ T cell expansion program to re-expand contracted clones in the tumor

Munetomo Takahashi, Mikiya Tsunoda, Hiroyasu Aoki…·Satoshi Ueha

This study identifies a transcriptomic signature predicting CD8+ T cell clone expansion rates and shows LAG-3 blockade reactivates this signature to re-expand contracted clones in tumors.

4 citations

mousescRNA-seq

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GenomicsCommunications BiologyPeer-reviewedJun 27, 2022

TAS-Seq: a robust and sensitive amplification method for bead-based scRNA-seq

Shigeyuki Shichino, Satoshi Ueha, Shinichi Hashimoto…·Kouji Matsushima

TAS-Seq improves scRNA-seq by enhancing gene detection and cell-cell interaction analysis in murine and human lung samples compared to existing methods.

47 citations

mousehuman

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