Author

Eiji Sugihara

Fujita Health UniversityORCID 0000-0002-3233-1045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Abhishek MaitiiD· 1 shared Andrea D. BedoyiD· 1 shared Bin WuiD· 1 shared Bing Z. CarteriD· 1 shared Chang-Yu CheniD· 1 shared Darah A Scruggs· 1 shared Dong CheniD· 1 shared Edward AyoubiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Abhishek MaitiORCID

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2 papers

Recent·Most cited

Dual MYC and GSPT1 Protein Degrader for MYC-Driven Cancers

Yuki Nishida, Valeria Impedovo, Edward Ayoub, Natalia Baran, Darah A Scruggs, Hideaki Mizuno, Shayaun Khazaei, Lauren B. Ostermann, Sandeep Singh, Andrea D. Bedoy, Po Yee Mak, Bing Z. Carter, Eiji Sugihara, Tetsuya Takimoto, Youzhi Tong, , Michael Andreeff

This paper identifies a novel MYC-GSPT1 feedback loop and reports a dual degrader, GT19630, that effectively targets MYC-driven cancers with anti-proliferative and apoptotic effects.

bioRxiv · Apr 24, 2025 · PreprintCancer Biology

TAS-Seq: a robust and sensitive amplification method for bead-based scRNA-seq

Shigeyuki Shichino, Satoshi Ueha, Shinichi Hashimoto, Tatsuro Ogawa, Hiroyasu Aoki, Bin Wu, Chang-Yu Chen, Masahiro Kitabatake, Noriko Ouji-Sageshima, Noriyoshi Sawabata, Takeshi Kawaguchi, Toshitugu Okayama, Eiji Sugihara, Shigeto Hontsu, Toshihiro Ito, , Kouji Matsushima

TAS-Seq improves scRNA-seq by enhancing gene detection and cell-cell interaction analysis in murine and human lung samples compared to existing methods.

Communications Biology · Jun 27, 2022Peer-reviewedGenomics