Author

Alex M. Li

University of PennsylvaniaORCID 0000-0001-7101-4547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abhishek Venketeswaran· 1 shared Anette U. DuensingiD· 1 shared Angelo AngioneiD· 1 shared Anthony Richard CilloiD· 1 shared Antonio Corral Tarbay· 1 shared Aparna Rao· 1 shared Arka N. MallelaiD· 1 shared Carly CardelloiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abhishek Venketeswaran

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1 paper

Recent·Most cited

All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis

Aparna Rao, Xiaoran Zhang, Anthony Richard Cillo, Jonathan Sussman, Poorva Sandlesh, Antonio Corral Tarbay, Arka N. Mallela, Carly Cardello, Katharine Krueger, Jessica A. Xu, Alex M. Li, Jason Z. Xu, Jonathan Patterson, Ebrar Akca, Angelo Angione, , Nduka Amankulor

This study shows that all-trans retinoic acid (ATRA) improves immune response in IDH-mutant gliomas by restoring the RA pathway, leading to tumor regression in mouse models and a clinical trial for human patients.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology