Author

Shih‐Han Lee

The University of Texas MD Anderson Cancer CenterORCID 0000-0001-7161-1157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Angela H. TingiD· 2 shared Adam Samuel SperlingiD· 1 shared Agata Sekrecka· 1 shared Briana A. SantoiD· 1 shared Byron LeeiD· 1 shared Christina S. LeslieiD· 1 shared Christine MayriD· 1 shared Cristian A. Otero-Perez· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Angela H. TingORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 4, 2025

A TP53 Intron-Derived Peptide Promotes Tumor Survival

Louis A. Cadena, Kevin Lee Luo, Sofia M. Fernandez…·Shih‐Han Lee

The paper identifies an intronic APA-derived protein, IPADP1, that promotes cancer cell survival and tumor formation in leukemia.

DOI 10.1101/2025.09.04.674312

humanproteomics

𝕏 PostBluesky

Systems BiologybioRxivPreprintMar 3, 2025

Alternative polyadenylation regulates human urothelial differentiation

N.T. Le, Surbhi Sona, Briana A. Santo…·Angela H. Ting

The paper investigates how alternative polyadenylation (APA) regulates urothelial differentiation using single-cell RNA-seq and spatial imaging, showing APA's role in shaping cell state-specific polyadenylation sites and transcriptome diversity.

DOI 10.1101/2025.03.03.641311

𝕏 PostBluesky

GenomicsNature CommunicationsPeer-reviewedApr 24, 2018

Widespread intronic polyadenylation diversifies immune cell transcriptomes

Irtisha Singh, Shih‐Han Lee, Adam Samuel Sperling…·Christina S. Leslie

The paper identifies widespread intronic polyadenylation (IpA) events in immune cells and shows their role in transcriptome diversification and potential functional consequences.

159 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky