Franziska Ragaller

Cell surface remodeling caused by the loss of flippase subunit TMEM30A in immune cells

This study investigates the effects of TMEM30A loss on immune cell membrane dynamics, revealing PS externalization, proteome reorganization, and glycocalyx remodeling with implications for immune therapy.

Studying macromolecular composition in cell-cell interfaces using 3D membrane reconstitution systems

This paper develops artificial and semi-artificial 3D membrane systems to study protein, lipid, and glycocalyx distribution at cell-cell interfaces, revealing differential partitioning and activation dynamics.

Prodan-based solvatochromic probes for polarity imaging of organelles

The paper introduces Prodan-based solvatochromic probes for imaging organelle polarity, showing organelle-specific polarity changes under starvation.

Image-based screens identify regulators of endogenous Dvl2 biomolecular condensates

The paper identifies regulators of Dvl2 biomolecular condensates using image-based screens and phosphoproteomics, finding CK1δ/ε inhibition blocks condensate formation and modulates Wnt signaling.

VISION -- an open-source software for automated multi-dimensional image analysis of cellular biophysics

VISION is an open-source software for automated multi-dimensional image analysis of cellular biophysics, enabling high throughput and correlative analysis of biophysical properties.