Karl T. Butterworth

This study shows FLASH irradiation reduces radiation-induced lymphopenia in mice by sparing circulating lymphocytes, with durable CD8 T cell preservation across proton and photon modalities.

This study identifies FLIP as a critical survival factor in KRAS-mutant lung cancers, revealing a KRAS-ERK-FLIP axis that protects against apoptosis and suggests FLIP as a therapeutic target.

This study shows that GIGYF2/4EHP-mediated translational repression helps maintain cellular homeostasis after ionizing radiation by preserving proteostasis and cell viability.

This study uses a multi-omics approach to analyze regional differences in cardiac responses to radiation, identifying distinct molecular and structural changes in different heart regions.