Zara Y. Weinberg

This study uses deep mutational pharmacology to show how different residues in the -opioid receptor determine the efficacy of opioids by shaping distinct activation mechanisms.

The paper characterizes small molecule and cell contact-inducible systems for controlling gene expression and differentiation in mouse embryonic stem cells.

This study demonstrates that de novo-designed minibinders can be adapted to various cell engineering tools, improving antigen detection and cytotoxicity compared to antibody-based systems.

This paper introduces SARSNotch, a sentinel cell system that detects SARS-CoV-2 Spike protein and triggers genetic responses in cell lines and T lymphocytes.

The paper identifies genes with biphasic expression in response to increasing cAMP levels and shows PKA and ERK1/2 exhibit opposite biphasic responses, revealing complex signaling integration.