Author

Matthew S. Kim

University of California, San FranciscoORCID 0000-0002-5836-8874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

Hana El‐SamadiD· 2 shared Wendell A. LimiD· 2 shared Andrew H. NgiD· 1 shared Devan H ShahiD· 1 shared Gavin E. Shavey· 1 shared Hersh K. BhargavaiD· 1 shared Irene P. CheniD· 1 shared Lucy S. ChongiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersSynthetic Biology

Hana El‐SamadORCID

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3 papers

Recent·Most cited

Degron-based bioPROTACs for controlling signaling in CAR T cells

Matthew S. Kim, Hersh K. Bhargava, Gavin E. Shavey, Wendell A. Lim, Hana El‐Samad, Andrew H. Ng

This paper introduces bioPROTACs, a genetic tool to control CAR T cell signaling by degrading specific proteins, demonstrating its effectiveness in inhibiting CAR signaling in human T cells.

ACS Synthetic Biology · Jul 11, 2024Peer-reviewedSynthetic Biology

De novo-designed minibinders expand the synthetic biology sensing repertoire

Zara Y. Weinberg, Sarah S. Soliman, Matthew S. Kim, Devan H Shah, Irene P. Chen, Mélanie Ott, Wendell A. Lim, Hana El‐Samad

This study demonstrates that de novo-designed minibinders can be adapted to various cell engineering tools, improving antigen detection and cytotoxicity compared to antibody-based systems.

bioRxiv · Jan 12, 2024 · PreprintSynthetic Biology

Engineering multiple levels of specificity in an RNA viral vector

Xiaojing J. Gao, Lucy S. Chong, Michaela H. Ince, Matthew S. Kim, Michael B. Elowitz

The paper demonstrates a viral delivery system with multiple control levels for targeted therapy using engineered components in a rabies virus model.

bioRxiv · May 27, 2020 · PreprintSynthetic Biology