Author

Eve J. Fine

Stanford MedicineORCID 0000-0001-7404-897XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ron O. DroriD· 2 shared Aashish ManglikiD· 1 shared Alem W. KahsaiiD· 1 shared Ali MasoudiiD· 1 shared Angus Li· 1 shared Arun Jyothidasan· 1 shared Balázs R. VargaiD· 1 shared Carl‐Mikael SuomivuoriiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Ron O. DrorORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 18, 2026

Distinct activation mechanisms underlie ligand efficacy at a GPCR

Marybeth Howard, Eve J. Fine, Karthik Srinivasan…·Willow Coyote‐Maestas

This study uses deep mutational pharmacology to show how different residues in the -opioid receptor determine the efficacy of opioids by shaping distinct activation mechanisms.

DOI 10.64898/2026.10.12.758633

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintJul 16, 2026

Conformational Basis of Functionally Selective Allosteric Modulation of the Angiotensin II type 1 Receptor by Small Molecules

Samuel Liu, Peng Xiao, Matthias Elgeti…·Robert J. Lefkowitz

The paper identifies and characterizes small molecule allosteric modulators of the AT1R, revealing their conformational mechanisms and effects on G protein and β-arrestin pathways.

DOI 10.64898/2026.07.15.736838

experimental assaydrug response / drug discovery

𝕏 PostBluesky