Emma Kaitlynn Allen

A funnel approach to enable analyses of epitope-specific human CD4 T cells specific for influenza and SARS-CoV-2.

The paper introduces a funnel approach to identify epitope-specific CD4 T cells for influenza and SARS-CoV-2 by narrowing down potential epitopes using HLA-DR transgenic mice and ELISpot assays.

High-dimensional multiomics reveals perturbations to IL-6/IL-6R axis and RUNX3 in CD4+ T cells during third trimester pregnancy

This study identifies changes in CD4+ T cell surface proteins and transcriptomes during pregnancy, highlighting perturbations in the IL-6/IL-6R axis and RUNX3 expression.

TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing

TIRTL-seq provides a scalable, cost-effective method for paired TCR repertoire sequencing, enabling accurate identification of TCR chain pairings and clonotype dynamics in large cohorts.

IL4i1-sourced oncometabolites promote neuroblastoma cell survival

This study shows that IL4i1 metabolites from immune cells suppress ferroptosis in neuroblastoma cells by scavenging free radicals and activating NRF2, promoting tumor survival.