Amélia Lalou

The paper identifies genetic and molecular regulators of lifespan in C. elegans using a recombinant inbred population and validates their relevance to human age-related diseases.

The paper integrates multi-omics data from two C. elegans strains to show that doxycycline-induced UPRmt affects mitochondrial function and lifespan through shared and strain-specific pathways.

The paper improves the ChEC-seq method to more accurately map transcription coactivators and transcription factors' genome-wide DNA binding sites.